Big white and black cat at mailing address of domain investor

Due to the high crime rate the domain investor does not live in her mailing address overnight. So many animals including humans and cats are criminally trespassing on the property
Since cats can carry covid-19 this can be dangerous.
The white and black cat is fairly large in size, and it runs away immediately after the domain investor enters the house, through the broken door, damaged by the burglars who ransacked the house in october 2018.
Any tips to prevent entry by cats will be greatly appreciated.